Decreased appetite can result from infections, gastrointestinal disorders, depression, anxiety, hormonal imbalances, chronic diseases such as Diabetes mellitus, or medication side effects. Acute illnesses like Influenza often suppress hunger due to inflammatory cytokine release. Pain, stress, and aging also alter appetite-regulating hormones such as ghrelin and leptin. Management depends on etiology: treat underlying infections, optimize chronic disease control, review medications, and ensure adequate hydration. Nutrient-dense small meals, appetite stimulants when indicated, and behavioral interventions can help. Pharmaceutical providers, including a reliable cephalexin capsules supplier, support infection management that may indirectly restore appetite once bacterial causes are resolved.